APC Anti-Human/Monkey CD14 Antibody[M5E2]

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£78.30

War £87.00

SKU:: E-AB-F1209E
Zusätzliche Namen:: CD14,Monocyte differentiation antigen CD14,Myeloid cell-specific leucine-rich glycoprotein
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD14
Klon:: M5E2
Uniprot:: P08571
Synonyme:: monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein
Weitere Details:: CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.