E-AB-F11880
Purified Anti-Mouse FcE EpsilonRIA Alpha Antibody[MAR-1], Functional Grade
Größe
£76.50
War £85.00
- SKU:
- E-AB-F11880
- Zusätzliche Namen:
- Fcr,Fcr-5,Fc-epsilon RI-alpha,fcepsilonri,FcERI,High affinity immunoglobulin epsilon receptor subunit alpha,Fce1a,Fcer1a
- Anwendung:
- Flow Cytometry
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Hamster
- Reaktivitäten:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse FcE EpsilonRIA Alpha protein
- Klon:
- MAR-1
- Uniprot:
- P20489
- Synonyme:
- fc-epsilon RI-alpha;FcE;Fce1;Fce1a;fcepsilonri;FcERI;Fcr-;Fcr-5;high affinity immunoglobulin epsilon receptor subunit alpha;igE Fc receptor subunit alpha
- Weitere Details:
- FcE EpsilonRIA Alpha is a transmembrane protein belonging to the Ig superfamily. FcE EpsilonRIA Alpha forms a tetrameric complex with one B Beta and two G Gamma-subunits. The FcE EpsilonRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcE EpsilonRIA Alpha, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcE EpsilonRIA Alpha subunit. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice