E-AB-F1159E
APC Anti-Human CD197/CCR7 Antibody[G043H7]
Größe
£108.00
War £120.00
- SKU:
- E-AB-F1159E
- Zusätzliche Namen:
- EBI1EVI1,CCR-7,CDw197,CMKBR7
- Anwendung:
- Flow Cytometry
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS
- Immunogen:
- CD197/CCR7
- Klon:
- G043H7
- Uniprot:
- P32248
- Synonyme:
- BLR2;Bukitt's lymphoma receptor 2;C-C chemokine receptor type 7;CC chemokine receptor 7;CC-CKR-7;CCR-7;CD197;CDw197;chemokine (C-C motif) receptor 7;CMKBR7;EBI1;EBV-induced G protein-coupled receptor 1;Epstein-Barr virus induced gene 1;Epstein-Barr virus-induced G-protein coupled receptor 1;lymphocyte-specific G protein-coupled peptide receptor;MIP-3 beta receptor
- Weitere Details:
- CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
- Versandbedingungen:
- Blue Ice