APC Anti-Human/Monkey CD11b Antibody[ICRF44]

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£66.60

War £74.00

SKU:: E-AB-F1146E
Zusätzliche Namen:: CD11 antigen-like family member B,CD11b,CR-3 alpha chain,Integrin alpha-M,Itgam,Leukocyte adhesion receptor MO1
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD11b
Klon:: ICRF44
Uniprot:: P11215
Synonyme:: antigen CD11b (p170);CD11 antigen-like family member B;CD11B;cell surface glycoprotein MAC-1 subunit alpha;complement component 3 receptor 3 subunit;CR-3 alpha chain;CR3A;integrin alpha-M;integrin, alpha M (complement component 3 receptor 3 subunit);leukocyte adhesion receptor MO1;MAC-1;MAC1A;macrophage antigen alpha polypeptide;macrophage-1 antigen alpha subunit;MO1A;Neutrophil adherence receptor;neutrophil adherence receptor alpha-M subunit;SLEB6
Weitere Details:: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as A AlphaMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin B Beta2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.