E-AB-F1131E
APC Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Größe
£83.70
War £93.00
- SKU:
- E-AB-F1131E
- Zusätzliche Namen:
- Programmed Death-1,PD-1
- Anwendung:
- Flow Cytometry
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- PBS
- Immunogen:
- CD279/PD-1
- Klon:
- 29F.1A12
- Uniprot:
- Q02242
- Synonyme:
- Ly101;mPD-1;PD-;PD-1;Pdc;Pdc1;programmed cell death 1 protein;programmed cell death protein 1;protein PD-1
- Weitere Details:
- CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
- Versandbedingungen:
- Blue Ice