APC Anti-Human CD35 Antibody[E11]

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£90.90

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SKU:: E-AB-F1062E
Zusätzliche Namen:: C3BR,C3b/C4b receptor,CD35,CR1,Complement receptor type 1
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD35
Klon:: E11
Uniprot:: P17927
Synonyme:: C3-binding protein;C3b/C4b receptor;C3BR;C4BR;CD35;CD35 antigen;complement component (3b/4b) receptor 1 (Knops blood group);complement receptor 1;complement receptor type 1;KN;Knops blood group antigen
Weitere Details:: CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.