PE Anti-Human CD45RA Antibody[HI100]

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£64.80

War £72.00

SKU:: E-AB-F1052D
Zusätzliche Namen:: CD45,L-CA,Ly-5,Ptprc,Receptor-type tyrosine-protein phosphatase C,T200
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS
Immunogen:: CD45RA
Klon:: HI100
Uniprot:: P08575
Synonyme:: B220;CD45;CD45 antigen;CD45R;GP180;L-CA;LCA;Leukocyte common antigen;LY5;protein tyrosine phosphatase, receptor type, c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen
Weitere Details:: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.