E-AB-F10280
Purified Anti-Mouse CD40 Antibody[FGK4.5/FGK45], Functional Grade
Größe
£80.10
War £89.00
- SKU:
- E-AB-F10280
- Zusätzliche Namen:
- B-cell surface antigen CD40,Bp50,CD40,CD40L receptor,Cd40,Tnfrsf5,Tumor necrosis factor receptor superfamily member 5
- Anwendung:
- Flow Cytometry
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD40 protein
- Klon:
- FGK4.5/FGK45
- Uniprot:
- P27512
- Synonyme:
- AI326936;B-cell surface antigen CD40;Bp5;Bp50;CD40L receptor;GP39;HIGM1;IGM;IMD3;p5;p50;T-BAM;T-cell differentiation antigen;Tnfr;Tnfrsf5;TRAP;tumor necrosis factor receptor superfamily member 5
- Weitere Details:
- CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice