E-AB-F10180
Purified Anti-Mouse CD54 Antibody[YN1/1.7.4], Functional Grade
Größe
£80.10
War £89.00
- SKU:
- E-AB-F10180
- Zusätzliche Namen:
- CD54,Icam-1,Icam1,Intercellular adhesion molecule 1,MALA-2,MyD10
- Anwendung:
- Flow Cytometry
- Konzentration:
- >= 1 mg/ml
- Aufreinigung:
- protein a/g purified
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- Immunogen:
- Recombinant Mouse CD54 protein
- Klon:
- YN1/1.7.4
- Uniprot:
- P13597
- Synonyme:
- CD54;Icam;Icam-1;intercellular adhesion molecule 1;Ly-4;Ly-47;MAL;MALA-2;myD10
- Weitere Details:
- CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Versandbedingungen:
- Blue Ice