APC Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

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£108.00

War £120.00

SKU:: E-AB-F1016E
Zusätzliche Namen:: Cd47,IAP,Integrin-associated protein,Leukocyte surface antigen CD47
Anwendung:: Flow Cytometry
Lagerbedingungen:: 2-8[o]C Do not freeze. Protect from light.
Hersteller:: Elabscience
Host:: Mouse
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS
Immunogen:: CD47
Klon:: MIAP410
Uniprot:: P97829, Q08722, Q61735
Synonyme:: 9130415E20Rik;AA407862;AI848868;antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;AW108519;B430305P08Rik;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;integrin-associated protein;integrin-associated signal transducer;It;Itgp;leukocyte surface antigen CD47;MER6;OA3;Protein MER6;Rh-related antigen
Weitere Details:: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPA Alpha, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.