E-AB-93272
IL-5 Polyclonal Antibody

Größe
£195.30
War £217.00
- SKU:
- E-AB-93272
- Zusätzliche Namen:
- nterleukin,Interleukin,IL5,EDF,IL-5,TRF,BCDFII,B-cell differentiation factor I,B-cell growth factor I,BCGF-II,Cytotoxic T-lymphocyte inducer,E-CSF,Eosinophil differentiation factor,ESGF,Interleukin-5,nterleukin-5,T-cell replacing factor
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human IL-5
- Uniprot:
- P05113
- Synonyme:
- B-cell differentiation factor I;colony-stimulating factor, eosinophil;EDF;eosinophil differentiation factor;IL-5;interleukin-5;T-cell replacing factor;TRF
- Weitere Details:
- This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
- Versandbedingungen:
- Blue Ice