E-AB-93220
GADD45A Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-93220
- Zusätzliche Namen:
- DDIT1,GADD45,GADD45A
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human GADD45A
- Uniprot:
- P24522
- Synonyme:
- DDIT-1;DDIT1;DNA damage-inducible transcript 1 protein;DNA damage-inducible transcript-1;GADD45;growth arrest and DNA damage-inducible protein GADD45 alpha;growth arrest and DNA-damage-inducible 45 alpha
- Weitere Details:
- This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice