E-AB-93211
HLA-DPB1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-93211
- Zusätzliche Namen:
- DP beta 1,DPB1,HLA-DP,HLA-DP1B,HLA-DPB,HLA-DPB1,class II,major histocompatibility complex
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human HLA-DPB1
- Uniprot:
- P04440
- Synonyme:
- DPB1;HLA class II histocompatibility antigen, DP beta 1 chain;HLA class II histocompatibility antigen, DP(W4) beta chain;HLA-DP;HLA-DP histocompatibility type, beta-1 subunit;HLA-DP1B;HLA-DPB;MHC class II antigen DPB1;MHC class II HLA-DP-beta-1;MHC HLA DPB1
- Weitere Details:
- HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice