E-AB-93120
IL4 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-93120
- Zusätzliche Namen:
- Interleukin,B-cell growth factor,BSF,IL4,BCGF-1,BCGF1,BSF-1,BSF1,IL-4,B-cell growth factor 1,B-cell IgG differentiation factor,B-cell stimulatory factor 1,Binetrakin,IGG1 induction factor,Interleukin-4,Lymphocyte stimulatory factor 1,Pitrakinra,IL2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human IL4
- Uniprot:
- P05112
- Synonyme:
- B cell growth factor 1;B_cell stimulatory factor 1;B-cell stimulatory factor 1;BCGF-1;BCGF1;binetrakin;BSF-1;BSF1;IL-4;interleukin 4 variant 2;interleukin-4;lymphocyte stimulatory factor 1;pitrakinra
- Weitere Details:
- The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Versandbedingungen:
- Blue Ice