Kdm6b Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-93093
Zusätzliche Namen:: JMJD3,KDM6B,Kdm6b
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of mouse Kdm6b
Weitere Details:: Enables beta-catenin binding activity, histone H3-tri/di-methyl-lysine-27 demethylase activity, and sequence-specific DNA binding activity. Involved in several processes, including histone H3-K27 demethylation, mesodermal cell differentiation, and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to hydrogen peroxide, histone demethylation, and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including brain, gut, liver, metanephros, and olfactory epithelium. Orthologous to human KDM6B (lysine demethylase 6B).