E-AB-92891
NPHP3 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-92891
- Zusätzliche Namen:
- CFAP31,MKS7,NPH3,NPHP3,RHPD,RHPD1,SLSN3
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human NPHP3
- Uniprot:
- Q7Z494
- Synonyme:
- CFAP31;cilia and flagella associated protein 31;Meckel syndrome, type 7;MKS7;nephrocystin-3;nephronophthisis 3 (adolescent);NPH3;RHPD;RHPD1;SLSN3
- Weitere Details:
- This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin, it is required for normal ciliary development, and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3, and also with renal-hepatic-pancreatic dysplasia, and Meckel syndrome type 7. Naturally occurring read-through transcripts exist between this gene and the downstream ACAD11 (acyl-CoA dehydrogenase family, member 11) gene.
- Versandbedingungen:
- Blue Ice