SSCA1/SerpinB3 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-92648
Zusätzliche Namen:: HsT1196,SCC,SCCA-1,SCCA-PD,SCCA1,SERPINB3,SSCA1,T4-A,serpin B3
Anwendung:: WB, IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SSCA1/SerpinB3
Uniprot:: P29508
Synonyme:: HsT1196;protein T4-A;SCC;SCCA-1;SCCA-PD;SCCA1;serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3;serpin B3;serpin peptidase inhibitor, clade B (ovalbumin), member 3;squamous cell carcinoma antigen 1;SSCA1;T4-A
Weitere Details:: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).