E-AB-92460
OGG1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-92460
- Zusätzliche Namen:
- HMMH,HOGG1,MUTM,OGG1,OGH1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human OGG1
- Uniprot:
- O15527
- Synonyme:
- 8-hydroxyguanine DNA glycosylase;AP lyase;DNA-apurinic or apyrimidinic site lyase;HMMH;HOGG1;MUTM;N-glycosylase/DNA lyase;OGG1 type 1f;OGH1
- Weitere Details:
- This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
- Versandbedingungen:
- Blue Ice