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E-AB-92378

(KO Validated) MSH2 Polyclonal Antibody

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£210.60

War £234.00

SKU:
E-AB-92378
Zusätzliche Namen:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2, mutS homolog 2,MSH2
Anwendung:
WB, IP
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human MSH2
Uniprot:
P43246
Synonyme:
COCA1;DNA mismatch repair protein Msh2;DNA mismatch repair protein Msh2 transcript;FCC1;hMSH2;HNPCC;HNPCC1;LCFS2;MMRCS2;mutS homolog 2, colon cancer, nonpolyposis type 1;MutS protein homolog 2
Weitere Details:
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice