ADRB2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-92258
Zusätzliche Namen:: ADRB2,ADRB2R,ADRBR,B2AR,BAR,BETA2AR
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human ADRB2
Uniprot:: P07550
Synonyme:: ADRB2R;ADRBR;adrenergic, beta-2-, receptor, surface;adrenoceptor beta 2 surface;B2AR;BAR;beta-2 adrenergic receptor;beta-2 adrenoceptor;beta-2 adrenoreceptor;BETA2AR;catecholamine receptor
Weitere Details:: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.