E-AB-92179
PCNT Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-92179
- Zusätzliche Namen:
- MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4,KEN
- Anwendung:
- WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PCNT
- Uniprot:
- O95613
- Synonyme:
- KEN;kendrin;MOPD2;PCN;PCNT2;PCNTB;PCTN2;pericentrin;pericentrin-2;pericentrin-380;pericentrin-B;SCKL4
- Weitere Details:
- The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice