E-AB-92099
TSN Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-92099
- Zusätzliche Namen:
- BCLF-1,C3PO,RCHF1,REHF-1,TBRBP,TRSLN,TSN,translin
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human TSN
- Uniprot:
- Q15631
- Synonyme:
- BCLF-1;C3PO;component 3 of promoter of RISC;RCHF1;recombination hotspot associated factor;recombination hotspot-binding protein;REHF-1;TBRBP;testis brain-RNA binding protein;translin;TRSLN
- Weitere Details:
- This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice