H2-Aa Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-92020
Zusätzliche Namen:: Aalpha,H-2Aa,H2-Aa,H2Aa,I-Aalpha,IAalpha,Ia-1,Ia1
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of mouse H2-Aa
Uniprot:: P14434
Synonyme:: A;Aalpha;H-2;H-2 class II histocompatibility antigen, A-B alpha chain;H-2 class II histocompatibility antigen, A-F alpha chain;H-2 class II histocompatibility antigen, A-K alpha chain;H-2 class II histocompatibility antigen, A-Q alpha chain;H-2 class II histocompatibility antigen, A-R alpha chain;H-2 class II histocompatibility antigen, A-S alpha chain;H-2 class II histocompatibility antigen, A-U alpha chain;H-2Aa;H2Aa;histocompatibility 2, class II antigen A, alpha;histocompatibility 2, class II antigen A, alpha, promoter 1;I;I-;I-Aalpha;Ia;Ia-1;Ia1;IAalpha;major histocompatibility protein class II alpha chain;MHC class II antigen alpha chain;MHC-II I-A(d) alpha
Weitere Details:: Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system, retina, and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple), gastrointestinal system cancer (multiple), glomerulonephritis (multiple), hematologic cancer (multiple), and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).

Versandbedingungen:: Blue Ice