ELOVL2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-91880
Zusätzliche Namen:: ELOVL2,SSC2
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human ELOVL2
Uniprot:: Q9NXB9
Synonyme:: 3-keto acyl-CoA synthase ELOVL2;elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2;elongation of very long chain fatty acids protein 2;ELOVL FA elongase 2;ELOVL fatty acid elongase 2;SSC2;very long chain 3-ketoacyl-CoA synthase 2;very long chain 3-oxoacyl-CoA synthase 2
Weitere Details:: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA, acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6 acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.