B4GALT3 Polyclonal Antibody

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£195.30

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SKU:: E-AB-91818
Zusätzliche Namen:: B4GALT3,beta-1,beta4Gal-T3
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human B4GALT3
Uniprot:: O60512
Synonyme:: b4Gal-T3;beta-1,4-galactosyltransferase 3;beta-1,4-GalTase 3;beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3;beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase;beta4Gal-T3;epididymis secretory sperm binding protein;N-acetyllactosamine synthase;nal synthase;neolactotriaosylceramide beta-1,4-galactosyltransferase;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3;UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3
Weitere Details:: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]

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