E-AB-91703
KAT6B Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-91703
- Zusätzliche Namen:
- GTPTS,KAT6B,MORF,MOZ2,MYST4,ZC2HC6B,qkf,querkopf
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human KAT6B
- Uniprot:
- Q8WYB5
- Synonyme:
- GTPTS;histone acetyltransferase KAT6B;histone acetyltransferase MORF;histone acetyltransferase MOZ2;histone acetyltransferase MYST4;K(lysine) acetyltransferase 6B;monocytic leukemia zinc finger protein-related factor;MORF;MOZ-related factor;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MOZ2;MYST histone acetyltransferase (monocytic leukemia) 4;MYST-4;MYST4;qkf;querkopf;ZC2HC6B
- Weitere Details:
- The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice