TBCE Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-91672
Zusätzliche Namen:: HRD,KCS,KCS1,PEAMO,TBCE,pac2
Anwendung:: IF
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TBCE
Uniprot:: Q15813
Synonyme:: HRD;hypoparathyroidism, growth and mental retardation, and dysmorphism;KCS;KCS1;pac2;PEAMO;Tubulin-folding cofactor E;tubulin-specific chaperone E
Weitere Details:: Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.