E-AB-91527
UBE2E2 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-91527
- Zusätzliche Namen:
- UBCH8,UBE2E2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human UBE2E2
- Uniprot:
- Q96LR5
- Synonyme:
- E2 ubiquitin-conjugating enzyme E2;UBCH8;ubiquitin carrier protein E2;ubiquitin conjugating enzyme E2E 2;ubiquitin-conjugating enzyme E2 E2;ubiquitin-conjugating enzyme E2E 2 (homologous to yeast UBC4/5);ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast);ubiquitin-protein ligase E2
- Weitere Details:
- Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96% identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.
- Versandbedingungen:
- Blue Ice