E-AB-91403
PGAM5 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-91403
- Zusätzliche Namen:
- BXLBV68,PGAM5
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PGAM5
- Uniprot:
- Q96HS1
- Synonyme:
- Bcl-XL-binding protein v68;BXLBV68;PGAM family member 5, serine/threonine protein phosphatase, mitochondrial;phosphoglycerate mutase family member 5;serine/threonine-protein phosphatase PGAM5, mitochondrial
- Weitere Details:
- Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
- Versandbedingungen:
- Blue Ice