E-AB-91385
NLRP10 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-91385
- Zusätzliche Namen:
- CLR11.1,NALP10,NLRP10,NOD8,PAN5,PYNOD
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human NLRP10
- Uniprot:
- Q86W26
- Synonyme:
- CLR11.1;NACHT, leucine rich repeat and PYD containing 10;NACHT, LRR and PYD domains-containing protein 10;NALP10;NOD8;nucleotide-binding oligomerization domain protein 8;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10;PAN5;PYNOD
- Weitere Details:
- Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
- Versandbedingungen:
- Blue Ice