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E-AB-91344

LONP2 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:
E-AB-91344
Zusätzliche Namen:
LONP,LONP2,LONPL,PLON,PSLON
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human LONP2
Uniprot:
Q86WA8
Synonyme:
lon protease 2;lon protease homolog 2, peroxisomal;lon protease-like protein 2;LONP;LONPL;Peroxisomal Lon protease;peroxisomal Lon protease homolog 2;peroxisomal LON protease like;PLON;PSLON
Weitere Details:
In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall peroxisome homeostasis as well as proteolytically degrading peroxisomal proteins damaged by oxidation. The protein has an N-terminal Lon N substrate recognition domain, an ATPase domain, a proteolytic domain, and, in some isoforms, a C-terminal peroxisome targeting sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Versandbedingungen:
Blue Ice