E-AB-91050
RRAGA Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-91050
- Zusätzliche Namen:
- FIP-1,FIP1,RAGA,RRAGA
- Anwendung:
- IHC, WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human RRAGA
- Uniprot:
- Q7L523
- Synonyme:
- adenovirus E3 14.7 kDa-interacting protein 1;adenovirus E3-14.7K interacting protein 1;FIP-1;FIP1;rag A;RAGA;ras-related GTP-binding protein A
- Weitere Details:
- Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.
- Versandbedingungen:
- Blue Ice