(KO Validated) CRMP2/DPYSL2 Polyclonal Antibody

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£210.60

War £234.00

SKU:: E-AB-90888
Zusätzliche Namen:: CRMP-2,CRMP2,DHPRP2,DPYSL2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2
Anwendung:: IHC, WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human CRMP2/CRMP2/DPYSL2
Uniprot:: Q16555
Synonyme:: Collapsin response mediator protein 2;collapsin response mediator protein hCRMP-2;CRMP-2;CRMP2;DHPRP2;dihydropyrimidinase-related protein 2;DRP-2;DRP2;N2A3;ULIP-2;ULIP2;unc-33-like phosphoprotein 2
Weitere Details:: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.