EMR2 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-90779
Zusätzliche Namen:: ADGRE2,CD312,EMR2,VBU
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human EMR2
Uniprot:: Q9UHX3
Synonyme:: adhesion G protein-coupled receptor E2;CD312;CD97;CD97 antigen;egf-like module containing, mucin-like, hormone receptor-like 2;EGF-like module receptor 2;EGF-like module-containing mucin-like hormone receptor-like 2;EMR2;Leukocyte antigen CD97;VBU
Weitere Details:: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.