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E-AB-90735

JARID1B Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:
E-AB-90735
Zusätzliche Namen:
CT31,JARID1B,KDM5B,PLU-1,PLU1,PPP1R98,PUT1,RBBP2H1A,RBP2-H1
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human JARID1B
Uniprot:
Q9UGL1
Synonyme:
[histone H3]-trimethyl-L-lysine(4) demethylase 5B;cancer/testis antigen 31;CT31;histone demethylase JARID1B;JARID1B;jumonji, AT rich interactive domain 1B;jumonji/ARID domain-containing protein 1B;lysine (K)-specific demethylase 5B;lysine-specific demethylase 5B;MRT65;PLU-1;PLU1;PPP1R98;protein phosphatase 1, regulatory subunit 98;PUT1;putative DNA/chromatin binding motif;RBBP2H1A;RBP2-H1;retinoblastoma-binding protein 2 homolog 1;retinoblastoma-binding protein 2, homolog 1A
Weitere Details:
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
Versandbedingungen:
Blue Ice