E-AB-90607
GLE1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-90607
- Zusätzliche Namen:
- GLE1,GLE1L,LCCS,LCCS1,hGLE1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GLE1
- Uniprot:
- Q53GS7
- Synonyme:
- CAAHC;CAAHD;GLE1 RNA export mediator homolog;GLE1-like protein;GLE1-like, RNA export mediator;GLE1L;hGLE1;LCCS;LCCS1;nucleoporin GLE1
- Weitere Details:
- This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice