LOXL4 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-90582
Zusätzliche Namen:: LOXC,LOXL4
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human LOXL4
Uniprot:: Q96JB6
Synonyme:: LOXC;lysyl oxidase homolog 4;lysyl oxidase related C;lysyl oxidase-like 4 pseudogene;lysyl oxidase-like protein 4;lysyl oxidase-related protein C
Weitere Details:: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.