E-AB-90565
MPZL1 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-90565
- Zusätzliche Namen:
- MPZL1,MPZL1b,PZR,PZR1b,PZRa,PZRb
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MPZL1
- Uniprot:
- O95297
- Synonyme:
- immunoglobulin family transmembrane protein;MPZL1b;myelin protein zero-like protein 1;protein zero related;Protein zero-related;PZR;PZR1b;PZRa;PZRb
- Weitere Details:
- Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
- Versandbedingungen:
- Blue Ice