FBXO31 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-90524
Zusätzliche Namen:: FBX14,FBXO14,FBXO31,Fbx31,MRT45,pp2386
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human FBXO31
Uniprot:: Q5XUX0
Synonyme:: F-box only protein 31;FBX14;Fbx31;FBXO14;MRT45;pp2386;putative breast cancer tumor-suppressor;SCF ubiquitin ligase specificity factor
Weitere Details:: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants.