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E-AB-90328

RNF4 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-90328
Zusätzliche Namen:
RES4-26,RNF4,SLX5,SNURF
Anwendung:
WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human RNF4
Uniprot:
P78317
Synonyme:
E3 ubiquitin ligase RNF4;E3 ubiquitin-protein ligase RNF4;RES4-26;RING finger protein 4;RING-type E3 ubiquitin transferase RNF4;SLX5;small nuclear RING finger protein;SNURF
Weitere Details:
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
Versandbedingungen:
Blue Ice