NLRP7 Polyclonal Antibody

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£195.30

War £217.00

SKU:: E-AB-90279
Zusätzliche Namen:: CLR19.4,HYDM,NALP7,NLRP7,NOD12,PAN7,PYPAF3
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human NLRP7
Uniprot:: Q8WX94
Synonyme:: CLR19.4;HYDM;NACHT, leucine rich repeat and PYD containing 7;NACHT, LRR and PYD containing protein 7;NACHT, LRR and PYD domains-containing protein 7;NALP7;NOD12;nucleotide-binding oligomerization domain protein 12;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7;PAN7;PYPAF3;PYRIN-containing Apaf1-like protein 3
Weitere Details:: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.