SOX4 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-90237
Zusätzliche Namen:: EVI16,SOX4,SRY-box 4
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human SOX4
Uniprot:: Q06945
Synonyme:: CSS10;ecotropic viral integration site 16;EVI16;SRY (sex determining region Y)-box 4;SRY-box 4;SRY-related HMG-box gene 4;transcription factor SOX-4
Weitere Details:: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.