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E-AB-90235

CRB1 Polyclonal Antibody

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£195.30

War £217.00

SKU:
E-AB-90235
Zusätzliche Namen:
CRB1,LCA8,RP12
Anwendung:
IHC, WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CRB1
Uniprot:
P82279
Synonyme:
CRB1-A;CRB1-B;CRB1-C;crumbs 1, cell polarity complex component;crumbs family member 1, photoreceptor morphogenesis associated;LCA8;protein crumbs homolog 1;RP12
Weitere Details:
This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.
Versandbedingungen:
Blue Ice