E-AB-90097
MED23 Polyclonal Antibody
Größe
£195.30
War £217.00
- SKU:
- E-AB-90097
- Zusätzliche Namen:
- ARC130,CRSP130,CRSP133,CRSP3,DRIP130,MED23,MRT18,SUR-2,SUR2
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MED23
- Uniprot:
- Q9ULK4
- Synonyme:
- 130 kDa transcriptional co-activator;133 kDa transcriptional co-activator;activator-recruited cofactor 130 kDa component;ARC130;cofactor required for Sp1 transcriptional activation subunit 3;CRSP130;CRSP133;CRSP3;DRIP130;Mediator complex subunit 23;mediator of RNA polymerase II transcription subunit 23;mental retardation, non-syndromic, autosomal recessive, 18;MRT18;Protein sur-2 homolog;SUR-2;SUR2;Transcriptional coactivator CRSP130;vitamin D3 receptor interacting protein;Vitamin D3 receptor-interacting protein complex 130 kDa component
- Weitere Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Versandbedingungen:
- Blue Ice