PIAS1 Polyclonal Antibody

Größe

£195.30

War £217.00

SKU:: E-AB-90060
Zusätzliche Namen:: DDXBP1,GBP,GU/RH-II,PIAS1,ZMIZ3
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PIAS1
Uniprot:: O75925
Synonyme:: AR interacting protein;DDXBP1;DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1;DEAD/H box-binding protein 1;E3 SUMO-protein ligase PIAS1;E3 SUMO-protein transferase PIAS1;GBP;gu-binding protein;GU/RH-II;protein inhibitor of activated STAT protein 1;RNA helicase II-binding protein;zinc finger, MIZ-type containing 3;ZMIZ3
Weitere Details:: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.