E-AB-81615
Recombinant Transmembrane Protein 173 Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-81615
- Zusätzliche Namen:
- ERIS,Endoplasmic reticulum interferon stimulator,FLJ38577,MITA,MPYS,Mediator of IRF3 activation,Mitochondrial mediator of IRF3 activation,N terminal methionine proline tyrosine serine plasma membrane tetra,endoplasmic reticulum IFN stimulator,hMITA,hSTING
- Anwendung:
- IHC, WB, IHC-P
- Konzentration:
- 300 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- Recombinant protein of human TMEM173
- Klon:
- R06-9A7
- Uniprot:
- Q86WV6
- Synonyme:
- endoplasmic reticulum IFN stimulator;endoplasmic reticulum interferon stimulator;ERIS;hMITA;hSTING;Mediator of IRF3 activation;MITA;mitochondrial mediator of IRF3 activation;MPYS;N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner;NET23;SAVI;stimulator of interferon genes protein;stimulator of interferon protein;STING;STING-beta;TMEM173;transmembrane protein 173
- Weitere Details:
- This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice