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E-AB-81613

Recombinant Tissue Factor Monoclonal Antibody

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£178.20

War £198.00

SKU:
E-AB-81613
Zusätzliche Namen:
CD142,CD142 antigen,Coagulation factor III,Coagulation factor III (thromboplastin tissue factor),F3,FLJ17960,TF,TFA,Thromboplastin,Tissue factor
Anwendung:
IHC, WB, IHC-P
Konzentration:
300 ug/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
A synthetic peptide of human Tissue Factor
Klon:
R04-7G2
Uniprot:
P13726
Synonyme:
CD142;Coagulation factor III;coagulation factor III (thromboplastin, tissue factor);TF;TFA;Thromboplastin;tissue factor
Weitere Details:
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Versandbedingungen:
Blue Ice