E-AB-81585
Recombinant NEDD4 Monoclonal Antibody
Größe
£178.20
War £198.00
- SKU:
- E-AB-81585
- Zusätzliche Namen:
- NEDD4,NEDD4-1,RPF1
- Anwendung:
- WB
- Konzentration:
- 300 ug/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
- Immunogen:
- A synthetic peptide of human NEDD4
- Klon:
- R06-7C3
- Uniprot:
- P46934
- Synonyme:
- cell proliferation-inducing gene 53 protein;E3 ubiquitin-protein ligase NEDD4;HECT-type E3 ubiquitin transferase NEDD4;NEDD4-1;Neural precursor cell expressed developmentally down-regulated protein 4;neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase;receptor-potentiating factor 1;RPF1
- Weitere Details:
- This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
- Versandbedingungen:
- Blue Ice