Recombinant mtTFA Monoclonal Antibody

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£178.20

War £198.00

SKU:: E-AB-81584
Zusätzliche Namen:: Mitochondrial transcription factor 1,MtTF1,TCF 6,TCF-6,TCF6,TCF6L1,TCF6L2,TCF6L3,TFAM,Tra,Transcription factor 6,Transcription factor 6 like 2 (mitochondrial transcription factor),anscription factor 6-like 1,mitochondrial transcription factor A,mtTFA
Anwendung:: IHC, WB, IHC-P, IF
Konzentration:: 300 ug/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:: A synthetic peptide of human mtTFA
Klon:: R08-3E2
Uniprot:: Q00059
Synonyme:: mitochondrial transcription factor 1;mitochondrial transcription factor A;MTDPS15;MTTF1;MTTFA;TCF6;TCF6L1;TCF6L2;TCF6L3;transcription factor 6;transcription factor 6-like 1;Transcription factor 6-like 2;transcription factor 6-like 2 (mitochondrial transcription factor);transcription factor 6-like 3;transcription factor A, mitochondrial
Weitere Details:: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.

Versandbedingungen:: Blue Ice