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E-AB-81572

Recombinant IMPDH2 Monoclonal Antibody

Größe

£178.20

War £198.00

SKU:
E-AB-81572
Zusätzliche Namen:
IMDH2,IMP (inosine monophosphate) dehydrogenase 2,IMP dehydrogenase 2,IMP oxireductase 2,IMPD 2,IMPD2,IMPDH 2,IMPDH II,IMPDH-II,Impdh2,Inosine 5' monophosphate dehydrogenase 2,Inosine 5' phosphate dehydrogenase 2,Inosine monophosphate dehydrogenase type I
Anwendung:
IHC, WB, IHC-P
Konzentration:
300 ug/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Immunogen:
A synthetic peptide of human IMPDH2
Klon:
R06-1B8
Uniprot:
P12268
Synonyme:
epididymis secretory sperm binding protein;IMP (inosine 5'-monophosphate) dehydrogenase 2;IMP (inosine monophosphate) dehydrogenase 2;IMP dehydrogenase II;IMP oxireductase 2;IMPD 2;IMPD2;IMPDH 2;IMPDH-II;inosine 5' phosphate dehydrogenase 2;inosine monophosphate dehydrogenase type II;inosine-5'-monophosphate dehydrogenase 2;inosine-5'-monophosphate dehydrogenase type II
Weitere Details:
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
Versandbedingungen:
Blue Ice